The King Lab

Choanoflagellates and the origin of animals

Publications

Robin B. Kodner, Roger E. Summons, Ann Pearson, Nicole King, and Andrew H. Knoll. (2008) Sterols in a unicellular relative of the metazoans. PNAS. doi:10.1073/pnas.0803975105

Wanqing Li, Susan L. Young, Nicole King, and W. Todd Miller. (2008) Signaling properties of a non-metazoan Src kinase and the evolutionary history of Src negative regulation. JBC. 283(22):15491-501.

Nicole King, M. Jody Westbrook*, Susan L. Young*, Alan Kuo, Monika Abedin, Jarrod Chapman, Stephen Fairclough, Uffe Hellsten, Yoh Isogai, Ivica Letunic, Michael Marr, David Pincus, Nicholas Putnam, Antonis Rokas, Kevin J. Wright, Richard Zuzow, William Dirks, Matthew Good, David Goodstein, Derek Lemons, Wanqing Li, Jessica Lyons, Andrea Morris, Scott Nichols, Daniel J. Richter, Asaf Salamov, JGI Sequencing, Peer Bork, Wendell A. Lim, Gerard Manning, W. Todd Miller, William McGinnis, Harris Shapiro, Robert Tjian, Igor V. Grigoriev, Daniel Rokhsar. (2008) The genome of the choanoflagellate Monosiga brevicollis and the origin of metazoans. Nature. 451: 783-788. Open access.

Monika Abedin and Nicole King. (2008) The premetazoan ancestry of cadherins. Science. 319(5865):946-948. Free access through this link.

Iñaki Ruiz-Trillo, Gertraud Burger, Peter W. H. Holland, Nicole King, B. Franz Lang, Andrew J. Roger and Michael W. Gray. (2007) The origins of multicellularity: a multi-taxon genome initiative. Trends in Genetics. 23(3):113-8. Pubmed

Nichols S.A., Dirks, W., Pearse, J.S., and King N. (2006) Early evolution of animal cell signaling and adhesion genes. PNAS. 103(33):12451-6. Pubmed

King, N. (2005) Choanoflagellates. Current Biology. 15(4):R113-4. Pubmed

King, N.(2004) The unicellular ancestry of animal development. Developmental Cell. 7: 313–325. Pubmed

Rokas, A., Williams, B.L., King, N., and Carroll, S.B. (2003) Genome scale approaches to resolving incongruence in molecular phylogenies. Nature. 425 (6960):798-804. Pubmed

King, N., Hittinger, C.T., and Carroll, S.B. (2003) Evolution of key cell signaling and adhesion protein families predates the origin of animals. Science. 301 (5631) : 361-363. Pubmed

Rokas, A.R., King, N., Finnerty, J.R., and Carroll, S.B. (2003) Conflicting phylogenetic signals at the base of the metazoan tree. Evolution and Development. 5(4): 346–359. Pubmed

King, N. (2002) Comparative biology and genomics join forces to decipher the diversity of life. Genome Biology. 3(8): reports4023.1-4023.2. Pubmed

King, N. and Carrroll, S.B. (2001) A receptor tyrosine kinase from choanoflagellates: Molecular insights into early animal evolution. PNAS. 98(26): 15032–15037. Pubmed