Publications

 For an up-to-date list of lab publications, please visit Pubmed or Google Scholar

 

1. Levin TC, Greaney AJ, Wetzel L, King N: The rosetteless gene controls development in the choanoflagellate S. rosetta. elife 2014, 3.

Highlighted in eLife Insight article:  Forward genetics for back-in-time questions by

2. Alegado RA, King N: Bacterial Influences on Animal Origins. Cold Spring Harb Perspect Biol 2014.

3. Beemelmanns C, Woznica A, Alegado RA, Cantley AM, King N, Clardy J: Synthesis of the rosette-inducing factor RIF-1 and analogs. J Am Chem Soc 2014, 136:10210–10213.

4. Dayel MJ, King N: Prey capture and phagocytosis in the choanoflagellate Salpingoeca rosetta. PLoS ONE 2014, 9:e95577.

5. Burkhardt P, Grønborg M, McDonald K, Sulur T, Wang Q, King N: Evolutionary insights into premetazoan functions of the neuronal protein homer. Mol Biol Evol 2014, 31:2342–2355.

6. Richter DJ, King N: The Genomic and Cellular Foundations of Animal Origins. Annu Rev Genet 2013, 47:527–555.

7. Levin TC, King N: Evidence for sex and recombination in the choanoflagellate Salpingoeca rosetta. Curr Biol 2013, 23:2176–2180.

8. McFall-Ngai M, Hadfield MG, Bosch TCG, Carey HV, Domazet-Loso T, Douglas AE, Dubilier N, Eberl G, Fukami T, Gilbert SF, Hentschel U, King N, Kjelleberg S, Knoll AH, Kremer N, Mazmanian SK, Metcalf JL, Nealson K, Pierce NE, Rawls JF, Reid A, Ruby EG, Rumpho M, Sanders JG, Tautz D, Wernegreen JJ: Animals in a bacterial world, a new imperative for the life sciences. Proc Natl Acad Sci USA 2013, 110:3229–3236.

9. Sebé-Pedrós A, Burkhardt P, Sánchez-Pons N, Fairclough SR, Lang BF, King N, Ruiz-Trillo I: Insights into the origin of metazoan filopodia and microvilli. Mol Biol Evol 2013, 30:2013–2023.

10. Fairclough SR, Chen Z, Kramer E, Zeng Q, Young S, Robertson HM, Begovic E, Richter DJ, Russ C, Westbrook MJ, Manning G, Lang BF, Haas B, Nusbaum C, King N: Premetazoan genome evolution and the regulation of cell differentiation in the choanoflagellate Salpingoeca rosetta. Genome Biol 2013, 14:R15.

11. Alegado RA, Grabenstatter JD, Zuzow R, Morris A, Huang SY, Summons RE, King N: Algoriphagus machipongonensis sp. nov. co-isolated with a colonial choanoflagellate. Int J Syst Evol Microbiol 2013, 63:163–168.

12. Nichols SA, Roberts BW, Richter DJ, Fairclough SR, King N: Origin of metazoan cadherin diversity and the antiquity of the classical cadherin/β-catenin complex. Proc Natl Acad Sci USA 2012, 109:13046–13051.

13. Alegado RA, Brown LW, Cao S, Dermenjian RK, Zuzow R, Fairclough SR, Clardy J, King N: A bacterial sulfonolipid triggers multicellular development in the closest living relatives of animals. elife 2012, 1:e00013.

14. Young SL, Diolaiti D, Conacci-Sorrell M, Ruiz-Trillo I, Eisenman RN, King N: Premetazoan ancestry of the Myc-Max network. Mol Biol Evol 2011, 28:2961–2971.

15. Dayel MJ, Alegado RA, Fairclough SR, Levin TC, Nichols SA, McDonald K, King N: Cell differentiation and morphogenesis in the colony-forming choanoflagellate Salpingoeca rosetta. Dev Biol 2011, 357:73–82.

16. Alegado RA, Ferriera S, Nusbaum C, Young SK, Zeng Q, Imamovic A, Fairclough SR, King N: Complete genome sequence of Algoriphagus sp. PR1, bacterial prey of a colony-forming choanoflagellate. J Bacteriol 2011, 193:1485–1486.

17. Abedin M, King N: Diverse evolutionary paths to cell adhesion. Trends Cell Biol 2010, 20:734–742.

18. King N: Nature and nurture in the evolution of cell biology. Mol Biol Cell 2010, 21:3801–3802.

19. Fairclough SR, Dayel MJ, King N: Multicellular development in a choanoflagellate. Curr Biol 2010, 20:R875–6.

20. Sebé-Pedrós A, Roger AJ, Lang FB, King N, Ruiz-Trillo I: Ancient origin of the integrin-mediated adhesion and signaling machinery. Proc Natl Acad Sci USA 2010, 107:10142–10147.

21. Nichols SA, Dayel MJ, King N: Genomic, phylogenetic, and cell biological insights into metazoan origins. In Animal Evolution: Genomes, Fossils, and Trees. Edited by Littlewood DTJ, Telford MJ. Oxford University Press; 2009.

22. King N, Young SL, Abedin M, Carr M, Leadbeater BS: Isolation of single choanoflagellate cells from field samples and establishment of clonal cultures. Cold Spring Harb Protoc 2009, 2009:pdb prot5147.

23. King N, Young SL, Abedin M, Carr M, Leadbeater BSC: Preparation of high-molecular-weight genomic DNA from Monosiga brevicollis and other choanoflagellates. Cold Spring Harb Protoc 2009, 2009:pdb.prot5153.

24. King N, Young SL, Abedin M, Carr M, Leadbeater BSC: Preparation of total RNA from Monosiga brevicollis and other choanoflagellates. Cold Spring Harb Protoc 2009, 2009:pdb.prot5151.

25. King N, Young SL, Abedin M, Carr M, Leadbeater BSC: Rapid preparation of genomic DNA from Monosiga brevicollis and other choanoflagellates. Cold Spring Harb Protoc 2009, 2009:pdb.prot5152.

26. King N, Young SL, Abedin M, Carr M, Leadbeater BSC: Starting and maintaining Monosiga brevicollis cultures. Cold Spring Harb Protoc 2009, 2009:pdb.prot5148.

27. King N, Young SL, Abedin M, Carr M, Leadbeater BSC: Visualizing the subcellular localization of actin, beta-tubulin, and DNA in Monosiga brevicollis. Cold Spring Harb Protoc 2009, 2009:pdb.prot5150.

28. King N, Young SL, Abedin M, Carr M, Leadbeater BSC: Separation of choanoflagellate and bacterial genomic DNA. Cold Spring Harb Protoc 2009, 2009:pdb.prot5154.

29. Grimson A, Srivastava M, Fahey B, Woodcroft BJ, Chiang HR, King N, Degnan BM, Rokhsar DS, Bartel DP: Early origins and evolution of microRNAs and Piwi-interacting RNAs in animals. Nature 2008, 455:1193–1197.

30. Kodner RB, Summons RE, Pearson A, King N, Knoll AH: Sterols in a unicellular relative of the metazoans. Proc Natl Acad Sci USA 2008, 105:9897–9902.

31. Li W, Young SL, King N, Miller WT: Signaling properties of a non-metazoan Src kinase and the evolutionary history of Src negative regulation. J Biol Chem 2008, 283:15491–15501.

32. Abedin M, King N: The premetazoan ancestry of cadherins. Science 2008, 319:946–948.

33. King N, Westbrook MJ, Young SL, Kuo A, Abedin M, Chapman J, Fairclough S, Hellsten U, Isogai Y, Letunic I, Marr M, Pincus D, Putnam N, Rokas A, Wright KJ, Zuzow R, Dirks W, Good M, Goodstein D, Lemons D, Li W, Lyons JB, Morris A, Nichols S, Richter DJ, Salamov A, Sequencing JGI, Bork P, Lim WA, Manning G, et al.: The genome of the choanoflagellate Monosiga brevicollis and the origin of metazoans. Nature 2008, 451:783–788.

34. Ruiz-Trillo I, Burger G, Holland PWH, King N, Lang BF, Roger AJ, Gray MW: The origins of multicellularity: a multi-taxon genome initiative. Trends Genet 2007, 23:113–118.

35. Nichols SA, Dirks W, Pearse JS, King N: Early evolution of animal cell signaling and adhesion genes. Proc Natl Acad Sci USA 2006, 103:12451–12456.

36. Carniol K, Ben-Yehuda S, King N, Losick R: Genetic dissection of the sporulation protein SpoIIE and its role in asymmetric division in Bacillus subtilis. J Bacteriol 2005, 187:3511–3520.

37. King N: Choanoflagellates. Curr Biol 2005, 15:R113–4.

38. King N: The unicellular ancestry of animal development. Dev Cell 2004, 7:313–325.

39. Rokas A, Williams BL, King N, Carroll SB: Genome-scale approaches to resolving incongruence in molecular phylogenies. Nature 2003, 425:798–804.

40. King N, Hittinger CT, Carroll SB: Evolution of key cell signaling and adhesion protein families predates animal origins. Science 2003, 301:361–363.

41. Rokas A, King N, Finnerty J, Carroll SB: Conflicting phylogenetic signals at the base of the metazoan tree. Evol Dev 2003, 5:346–359.

42. King N: Comparative biology and genomics join forces to decipher the diversity of life. Genome Biol 2002, 3:REPORTS4023.

43. King N, Carroll SB: A receptor tyrosine kinase from choanoflagellates: molecular insights into early animal evolution. Proc Natl Acad Sci USA 2001, 98:15032–15037.

44. King N, Dreesen O, Stragier P, Pogliano K, Losick R: Septation, dephosphorylation, and the activation of sigma(F) during sporulation in Bacillus subtilis. Genes Dev 1999, 13:1156–1167.

45. Widmer J, Fassihi KS, Schlichter SC, Wheeler KS, Crute BE, King N, NutileMcMenemy N, Noll WW, Daniel S, Ha J, Kim KH, Witters LA: Identification of a second human acetyl-CoA carboxylase gene. Biochem J 1996, 316:915–922.

46. Gindhart JG, King AN, Kaufman TC: Characterization of the Cis-Regulatory Region of the Drosophila Homeotic Gene Sex Combs Reduced. Genetics 1995, 139:781–795.

47. Witters LA, Widmer J, King AN, Fassihi K, Kuhajda F: Identification of Human Acetyl-Coa Carboxylase Isozymes in Tissue and in Breast-Cancer Cells. Int J Biochem 1994, 26:589–594.

48. Witters LA, Christensen A, Fassihi K, King AN, Widmer J, Quistorff B: Application of dual-digitonin-pulse perfusion to the study of hepatic mRNA zonation. Biochem J 1993, 294 ( Pt 3):809–812.