Publications

For an up-to-date list of lab publications, please also visit Google Scholar.

Woznica A, King N: Lessons from simple marine models on the bacterial regulation of eukaryotic development. Current Opinion in Microbiology 2018, 43: 108-116.

Richter DJ, Fozouni P, Eisen M, King N: Gene family innovation, conservation and loss on the animal stem lineage. eLife 2018, 7:e34226.

Wetzel L, Levin T, Hulett RE, Chan D, King G, Aldayafleh R, Booth D, Sigg MA, King N: Glycosyltransferases promote development and prevent promiscuous cell aggregation in the choanoflagellate S. rosetta. bioRxiv 2018, 384453.

Booth D, Middleton H, King N: Choanoflagellate transfection illuminates their cell biology and the ancestry of animal septins. bioRxiv 2018, 343111.

Brunet T, King N: The origin of animal multicellularity and cell differentiation. Developmental Cell 2017, 43: 124–140.

King N, Rokas A: Embracing Uncertainty in Reconstructing Early Animal Evolution. Current Biology 2017, 27 (19): R1081-R1088.

Woznica A, Gerdt P, Hulett RE, Clardy J, King N: Mating in the Closest Living Relatives of Animals Is Induced by a Bacterial Chondroitinase. Cell 2017, 170: 1059-1061.

Simion P, Philippe H, Baurain D, Jager M, Richter DJ, Di Franco A, Roure B, Satoh N, Quéinnec É, Ereskovsky A, Lapébie P, Corre E, Delsuc F, King N, Wörheide G, Manuel M: A Large and Consistent Phylogenomic Dataset Supports Sponges as the Sister Group to All Other Animals. Current Biology 2017, 27: 958-967.

Marron AO,Ratcliffe S, Wheeler GL, Goldstein RE, King N, Not F, De Vargas C, Richter DJ: The Evolution of Silicon Transport in Eukaryotes. Molecular Biology and Evolution 2016, 33 (12): 3226-3248.

Miño GL, Koehl M, King N, Stocker R: Finding patches in a heterogeneous aquatic environment: pH‐taxis by the dispersal stage of choanoflagellates. Limnology and Oceanography Letters 2017, 2 (2): 37-46.

Goldstein B, King N: The Future of Cell Biology: Emerging Model Organisms. Trends in Cell Biology 2016. 26 (11): 818-824.

Arendt D, King N, Carroll SB, Wittkopp P, Koonin E, Kruglyak L: Big questions in evolution. Cell 2016, 166.

Woznica A, Cantley AM, Beemelmanns C, Freinkman E, Clardy J, King N: Bacterial lipids activate, synergize, and inhibit a developmental switch in choanoflagellates. Proceedings of the National Academy of Sciences 2016, 113 (29): 7894-7899.

Booth DS, King N: Gene regulation in transition. Nature 2016, 534 (7608): 482-484.

Cantley AM, Woznica A, Beemelmanns C, King N, Clardy J: Isolation and synthesis of a bacterially produced inhibitor of rosette development in choanoflagellates. Journal of the American Chemical Society 2016, 138 (29): 4326-4329.

Anderson DP, Whitney DS, Hanson-Smith V, Woznica A, Campodonico-Burnett W, Volkman BF, King N, Thornton JW, Prehoda KE: Evolution of an ancient protein function involved in organized multicellularity in animals. Elife 2016, 5: e10147.

King N, Müller S: Environmental microbiology: Revisiting the physiology of microorganisms on the single cell scale. Current Opinion in Microbiology 2015, 25: v-vi.

Levin TC, Greaney AJ, Wetzel L, King N: The rosetteless gene controls development in the choanoflagellate S. rosetta. eLife 2014, 3.

Alegado RA, King N: Bacterial influences on animal origins. Cold Spring Harbor perspectives in biology 2014, a016162.

Beemelmanns C, Woznica A, Alegado RA, Cantley AM, King N, Clardy J: Synthesis of the rosette-inducing factor RIF-1 and analogs. Journal of the American Chemical Society 2014, 136 (29): 10210-10213.

Burkhardt P, Grønborg M, McDonald K, Sulur T, Wang Q, King N: Evolutionary insights into premetazoan functions of the neuronal protein Homer. Molecular Biology and Evolution 2014, msu178.

Dayel MJ, King N: Prey Capture and Phagocytosis in the Choanoflagellate Salpingoeca rosetta. PloS one 2014, 9 (5): e95577.

Richter DJ, King N: The Genomic and Cellular Foundations of Animal Origins. Annual review of genetics 2013, 47: 509-537.

Levin TC, King N: Evidence for Sex and Recombination in the Choanoflagellate Salpingoeca rosetta. Current Biology 2013, 23 (21): 2176-2180.

Sebé-Pedrós A, Burkhardt P, Sánchez-Pons N, Fairclough SR, Lang BF, King N, Ruiz-Trillo I: Insights into the origin of metazoan filopodia and microvilli. Molecular biology and evolution 2013, 30 (9): 2013-2023.

McFall-Ngai M, Hadfield MG, Bosch T CG, Carey HV, Domazet-Lošo T, Douglas AE, Dubilier N, Eberl G, Fukami T, Gilbert SF, Hentschel U, King N, Kjelleberg S, Knoll AH, Kremer N, Mazmanian SK, Metcalf JL, Nealson K, Pierce NE, Rawls JF, Reid A, Ruby EG, Rumpho M, Sanders JG, Tautz D, Wernegreen JJ: Animals in a bacterial world, a new imperative for the life sciences. Proceedings of the National Academy of Sciences 2013, 110 (9): 3229-3236.

Fairclough SR, Chen Z, Kramer E, Zeng Q, Young S, Robertson HM, Begovic E, Richter DJ, Russ C, Westbrook MJ, Manning G, Lang BF, Haas B, Nusbaum C, King N: Premetazoan genome evolution and the regulation of cell differentiation in the choanoflagellate Salpingoeca rosetta. Genome Biology 2013, 14 (2): R15.

Alegado RA, Brown LW, Cao S, Dermenjian RK, Zuzow R, Fairclough SR, Clardy J, King N: A bacterial sulfonolipid triggers multicellular development in the closest living relatives of animals. Elife 2012, 1.

Nichols SA, Roberts BW, Richter DJ, Fairclough SR, King N:Origin of metazoan cadherin diversity and the antiquity of the classical cadherin/β-catenin complex. Proceedings of the National Academy of Sciences 2012, 109 (32): 13046-13051.

Alegado RA, Grabenstatter JD, Zuzow R, Morris A, Huang SY, Summons RE, King N: Algoriphagus machipongonensis sp. nov. co-isolated with a colonial choanoflagellate. International Journal of Systematic and Evolutionary Microbiology 2012.

Young SL, Diolaiti D, Conacci-Sorrell M, Ruiz-Trillo I, Eisenman RE, King N: Premetazoan Ancestry of the Myc–Max Network. Molecular Biology and Evolution 2011, 28 (10): 2961-2971.

Dayel MJ, Alegado RA, Fairclough SR, Levin TC, Nichols SA, McDonald K, King N: Cell differentiation and morphogenesis in the colony-forming choanoflagellate Salpingoeca rosetta. Developmental biology 2011, 357 (1): 73-82.

Alegado RA, Ferriera S, Nusbaum C, Young SK, Zeng Q, Imamovic A, Fairclough SR, King N: Complete genome sequence of Algoriphagus sp. PR1, bacterial prey of a colony-forming choanoflagellate. Journal of bacteriology 2011, 193 (6): 1485-1486.

Abedin M, King N: Diverse evolutionary paths to cell adhesion. Trends in cell biology 2010, 20 (12): 734-742.

King N: Nature and nurture in the evolution of cell biology. Molecular biology of the cell 2010. 21 (22): 3801-3802.

Fairclough SR, Dayel MJ, King N: Multicellular development in a choanoflagellate. Current Biology 2010, 20 (20): R875-R876.

King N, Young SL, Abedin M, Carr M, Leadbeater BSC: Preparation of total RNA from Monosiga brevicollis and other choanoflagellates. Cold Spring Harbor Protocols 2009, 2009 (2): pdb. prot5151.

King N, Young SL, Abedin M, Carr M, Leadbeater BSC: Isolation of single choanoflagellate cells from field samples and establishment of clonal cultures. Cold Spring Harbor Protocols 2009, 2009 (2): pdb. prot5147.

King N, Young SL, Abedin M, Carr M, Leadbeater BSC: Rapid preparation of genomic DNA from Monosiga brevicollis and other choanoflagellates. Cold Spring Harbor Protocols 2009, 2009 (2): pdb. prot5152.

King N, Young SL, Abedin M, Carr M, Leadbeater BSC: Visualizing the Subcellular Localization of Actin, β-Tubulin, and DNA in Monosiga brevicollis. Cold Spring Harbor Protocols 2009, 2009 (2): pdb. prot5150.

King N, Young SL, Abedin M, Carr M, Leadbeater BSC: Long-term frozen storage of choanoflagellate cultures. Cold Spring Harbor Protocols 2009, 2009 (2): pdb. prot5149.

Nichols SA, Dayel MJ, King N: Genomic, phylogenetic and cell biological insights into metazoan origins. Animal evolution: Genomes, fossils and trees 2009, 24-32.

Sebé-Pedrós A, Roger AJ, Lang FB, King N, Ruiz-Trillo I: Ancient origin of the integrin-mediated adhesion and signaling machinery. Proceedings of the National Academy of Sciences 2010, 107 (22): 10142-10147.

King N, Young SL, Abedin M, Carr M, Leadbeater BSC: Separation of choanoflagellate and bacterial genomic DNA. Cold Spring Harbor Protocols 2009, 2009 (2): pdb. prot5154.

King N, Young SL, Abedin M, Carr M, Leadbeater BSC: Preparation of high-molecular-weight genomic DNA from Monosiga brevicollis and other choanoflagellates. Cold Spring Harbor Protocols 2009, 2009 (2): pdb. prot5153.

King N, Young SL, Abedin M, Carr M, Leadbeater BSC: Starting and maintaining Monosiga brevicollis cultures. Cold Spring Harbor Protocols 2009, 2009 (2): pdb. prot5148.

Ruiz-Trillo I, Burger G, Holland PWH, King N, Lang BF, Roger AJ, Gray MW: The origins of multicellularity: a multi-taxon genome initiative. TRENDS in Genetics 2007, 23 (3): 113-118.

Li W, Young SL, King N, Miller WT: Signaling properties of a non-metazoan Src kinase and the evolutionary history of Src negative regulation. Journal of Biological Chemistry 2008, 283 (22): 15491-15501.

Kodner RB, Summons RE, Pearson A, King N, Knoll AH: Sterols in a unicellular relative of the metazoans. Proceedings of the National Academy of Sciences 2008, 105 (29): 9897-9902.

Grimson A, Srivastava M, Fahey B, Woodcroft BJ, Chiang HR, King N, Degnan BM, Rokhsar DS, Bartel DP: Early origins and evolution of microRNAs and Piwi-interacting RNAs in animals. Nature 2008, 455 (7217): 1193-1197.

King N, Young SL, Abedin M, Carr M, Leadbeater BSC: The choanoflagellates: Heterotrophic nanoflagellates and sister group of the metazoa. Cold Spring Harbor Protocols 2009, 2009 (2): pdb. emo116.

Abedin M, King N: The premetazoan ancestry of cadherins. Science 2008, 319 (5865): 946-948.

Ruiz-Trillo I, Burger G, Holland PWH, King N, Lang BF, Roger AJ, Gray MW: The origins of multicellularity: a multi-taxon genome initiative. TRENDS in Genetics 2007, 23 (3): 113-118.

Nichols SA, Dirks W, Pearse JS, King N: Early evolution of animal cell signaling and adhesion genes. Proceedings of the National Academy of Sciences 2006, 103 (33): 12451-12456.

Carniol K, Ben-Yehuda S, King N, Losick R: Genetic dissection of the sporulation protein SpoIIE and its role in asymmetric division in Bacillus subtilis. Journal of bacteriology 2005, 187 (10): 3511-3520.

King, N: Choanoflagellates. Current Biology 2005, 15(4): R113-R114.

King N: The unicellular ancestry of animal development. Developmental cell 2004, 7 (3): 313-325.

Rokas A, Williams BL, King N, Carroll SB: Genome-scale approaches to resolving incongruence in molecular phylogenies. Nature 2003, 425 (6960): 798-804.

King N, Hittinger CT, Carroll SB: Evolution of key cell signaling and adhesion protein families predates animal origins. Science 301 (5631): 361-363.

Rokas A, King N, Finnerty J, Carroll SB: Conflicting phylogenetic signals at the base of the metazoan tree. Evolution & development 2003, 5 (4): 346-359.

King N: Comparative biology and genomics join forces to decipher the diversity of life. Genome Biology 2002, 3 (8): reports4023.

King N, Carroll SB: A receptor tyrosine kinase from choanoflagellates: molecular insights into early animal evolution. Proceedings of the National Academy of Sciences 2001, 98 (26): 15032-15037.

King N, Dreesen O, Stragier P, Pogliano K, Losick R: Septation, dephosphorylation, and the activation of ςF during sporulation in Bacillus subtilis. Genes & development 1999, 13 (9): 1156-1167.

King N: Linking gene expression to morphogenesis. 1999.

Widmer J, Fassihi K, Schlichter S, Wheeler K, Crute B, King N, Nutile-McMenemy N, Noll W, Daniel S, Ha J, Kim K, Witters L: Identification of a second human acetyl-CoA carboxylase gene. Biochem. J 1996, 316: 915-922.

Gindhart JG, King AN, Kaufman TC: Characterization of the cis-regulatory region of the Drosophila homeotic gene Sex combs reduced. Genetics 1995, 139 (2): 781-795.

Witters LA, Widmer J, King AN, Fassihi K, Kuhajda F: Identification of human acetyl-CoA carboxylase isozymes in tissue and in breast cancer cells. The International journal of biochemistry 1994, 26 (4): 589-594.

Fairclough S, King N: Choanoflagellida, collared-flagellates.

Witters LA, Christensen A, Fassihi K, King AN, Widmer J , Quistorff B: Application of dual-digitonin-pulse perfusion to the study of hepatic mRNA zonation. Biochemical Journal 1993, 294 (pt 3): 809.